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Oral metronidazole has become jnetoto reported to potenti-ate the anticoagulant impact of coumarin and warfarin leading to a prolongation of prothrombin time. The result of topical metronida-zole on prothrombin time is not known.
Fertility experiments are already performed in mice up to six moments the recommended human oral dose (determined by mg/m²) and have uncovered no evidence of impaired fertility.
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While these reduced levels of publicity are less likely to supply the frequent reactions found with oral metronidazole, the potential for these and also other reactions can not be excluded presently.
Oral metronidazole has actually been documented to potentiate the anticoagulant influence of warfarin and also other coumarin jnetoto anticoagulants, resulting in a prolongation of prothrombin time.